netMUG: a novel network-guided multi-view clustering workflow for dissecting genetic and facial heterogeneity

Introduction: Multi-view data offer advantages over single-view data for characterizing individuals, which is crucial in precision medicine toward personalized prevention, diagnosis, or treatment follow-up.Methods: Here, we develop a network-guided multi-view clustering framework named netMUG to identify actionable subgroups of individuals.This pip

read more


Engineering exosomes by three-dimensional porous scaffold culture of human umbilical cord mesenchymal stem cells promote osteochondral repair

Improving the poor microenvironment in the joint cavity has potential for treating cartilage injury, and mesenchymal stem cell (MSC)-derived exosomes (MSC-Exos), which can modulate cellular behavior, are becoming a new cell-free therapy for cartilage repair.Here, we used acellular cartilage extracellular matrix (ACECM) to prepare 3D scaffolds and 2

read more

Bio-reconstruction of root canal using dentin post

This case report describes the successful management of complicated crown fracture of left maxillary central incisor (#21) of 23-year-old male using dentin (biological) post made from human tooth.Endodontic treatment was initiated and sectional obturation was done using ProTaper gutta-percha and AH Plus sealer.The coronal space was modified to rece

read more