Introduction: Multi-view data offer advantages over single-view data for characterizing individuals, which is crucial in precision medicine toward personalized prevention, diagnosis, or treatment follow-up.Methods: Here, we develop a network-guided multi-view clustering framework named netMUG to identify actionable subgroups of individuals.This pip
Precision carving of costal cartilage graft for contour fill in aesthetic and reconstructive rhinoplasty
Background: Autogenous costal cartilage is a good option for large volume requirements in rhinoplasty, when septal or conchal cartilages do not suffice.Reluctance to use costal cartilage is due to apprehension of warping.However, warping can be avoided if we follow the principle of balanced section as advocated by Gibson and Davis."Warping" can als
Engineering exosomes by three-dimensional porous scaffold culture of human umbilical cord mesenchymal stem cells promote osteochondral repair
Improving the poor microenvironment in the joint cavity has potential for treating cartilage injury, and mesenchymal stem cell (MSC)-derived exosomes (MSC-Exos), which can modulate cellular behavior, are becoming a new cell-free therapy for cartilage repair.Here, we used acellular cartilage extracellular matrix (ACECM) to prepare 3D scaffolds and 2
Bio-reconstruction of root canal using dentin post
This case report describes the successful management of complicated crown fracture of left maxillary central incisor (#21) of 23-year-old male using dentin (biological) post made from human tooth.Endodontic treatment was initiated and sectional obturation was done using ProTaper gutta-percha and AH Plus sealer.The coronal space was modified to rece
Dynamics simulation research on fault conditions of deflecting to airflow flap mechanism of civil aircraft
The deflecting to airflow flap of civil aircraft are generally driven by complex multi-hinge mechanisms in space.According to the requirements of the airworthiness clause CCAR25.671, it is necessary to carry out research on the mechanism characteristics under typical faults.Firstly, a digital prototype of the mechanism motion is constructed, Makeup